Metal Nanomaterial Toxicity Variations Within the Vascular System
نویسندگان
چکیده
منابع مشابه
The vascular system as a target of metal toxicity.
Vascular system function involves complex interactions among the vascular endothelium, smooth muscle, the immune system, and the nervous system. The toxic metals cadmium (Cd), arsenic (As), and lead (Pb) can target the vascular system in a variety of ways, ranging from hemorrhagic injury to subtle pathogenic remodeling and metabolic changes. Acute Cd exposure results in hemorrhagic injury to th...
متن کاملMetal toxicity in the central nervous system.
The nervous system is the principal target for a number of metals. Inorganic compounds of aluminum, arsenic, lead, lithium, manganese, mercury, and thallium are well known for their neurological and behavioral effects in humans. The alkyl derivatives of certain metals--lead, mercury and tin--are specially neurotoxic. Concern over human exposure and in some cases, outbreaks of poisoning, have st...
متن کاملIn vitro assessments of nanomaterial toxicity.
Nanotechnology has grown from a scientific interest to a major industry with both commodity and specialty nanomaterial exposure to global populations and ecosystems. Sub-micron materials are currently used in a wide variety of consumer products and in clinical trials as drug delivery carriers and imaging agents. Due to the expected growth in this field and the increasing public exposure to nano...
متن کاملMetal Oxide Nanomaterial QNAR Models: Available Structural Descriptors and Understanding of Toxicity Mechanisms
Metal oxide nanomaterials are widely used in various areas; however, the divergent published toxicology data makes it difficult to determine whether there is a risk associated with exposure to metal oxide nanomaterials. The application of quantitative structure activity relationship (QSAR) modeling in metal oxide nanomaterials toxicity studies can reduce the need for time-consuming and resource...
متن کاملLinking nanomaterial physico - chemical properties with cellular uptake and toxicity
Nanotechnology is one of the key technologies of the 21st century. Already by now, many products containing manufactured nanomaterials (NMs) have entered the market. Most industrial applications are based on just a few NM types, mostly metals and metal oxides. However, by varying size, shape or surface chemistry a large number of variants can be produced. Variations of physico-chemical paramete...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Environmental Health Reports
سال: 2016
ISSN: 2196-5412
DOI: 10.1007/s40572-016-0112-1